Case Study
Assessing indirect costs and productivity loss in oncology
Objectives: To compile evidence on productivity losses and potential reduction of indirect costs associated with an oncology indication
Research
- Evidence was compiled through literature searches with respect to productivity losses/indirect costs in oncology
- Reviewed trial data
- Relevant phase III trials were reviewed to assess clinical outcomes and population characteristics suggesting economic benefits due to reduced productivity losses
- Collaboration with KOLs
- Clinical experts were consulted regarding primary study findings/patient population assumptions and potential reductions in productivity loss
Analyze
- Based on data retrieved from various sources (literature, e-databases, and experts), evidence tables were created to populate a deterministic model which would calculate cost savings due to reduced productivity-loss following oncology treatments
- Country-specific patient population figures were derived through incident cases from cancer registries
- Clinical outcomes from phase III trials as well as evidence from secondary sources were applied to incident cases
- Potential cost savings in patients who return to work were analyzed using the human capital approach
Communicate
- Evidence from the literature:
- A comprehensive presentation was created for the client's internal communication
- Prepared abstract and poster presentation for a conference
- Results from the cost analysis were presented in abstracts and a scientific manuscript
- Abstracts were accepted for presentation at a major European conference
- The manuscript was published in a leading oncology journal
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