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Appraisal of the disease burden within a rheumatic indication in 5 key EU countries

Objectives: To identify an unmet need for effective treatment options due to better efficacy and less adverse events

Research

  • Data searches were conducted through a systematic literature search and a supplementary internet search
  • The following data were gathered:
    • Epidemiology
    • Humanistic burden (quality of life)
    • Medical burden (direct and indirect cost)
  • Scope
    • France, Italy, Germany, Spain, and the UK
  • Data were evaluated with respect to validity and eligibility for the planned cost calculation

Analyze

  • Cost of illness calculations for each country were performed based on the retrieved data
  • Additionally, expert interviews were conducted to fill gaps/confirm findings and assumptions

Appraisal of the disease burden - Analyze

Communicate

  • The comprehensive cost-of-illness report included a detailed explanation of the methodology and a list of sources used
  • A separate Excel document containing a summary of the cost calculations in a user-friendly interface was also developed

Appraisal of the disease burden  - Communicate